The winery is owned and operated by Salvatore Martusciello and his wife, Gilda Guida. Salvatore hails from a family with deep roots in Campanian viticulture; his uncle, Gennaro Martusciello, was instrumental in achieving DOC status for several regional wines, including Asprinio d’Aversa. Gilda actively participates in the winery's operations, and their son, Francesco Martusciello Jr., contributes as the oenologist, ensuring the continuation of the family's winemaking legacy.

Although the Salvatore Martusciello winery was established in 2015, the Martusciello family's involvement in Campanian winemaking spans generations. Salvatore and Gilda founded the winery to continue their family's tradition of producing wines that reflect the unique terroir of Campania. Their efforts have been pivotal in revitalizing interest in indigenous grape varieties and traditional cultivation methods, particularly the alberata system for Asprinio d’Aversa.

The winery is located in Pozzuoli, within the Campi Flegrei area of Campania, a region characterized by its volcanic soils and proximity to the Tyrrhenian Sea. Their vineyards are situated across three key areas: the Sorrento Peninsula, Campi Flegrei, and Agro Aversano. These locations fall within several DOC zones, including Campi Flegrei DOC, Penisola Sorrentina DOC, and Aversa DOC, each contributing distinct characteristics to the wines produced

The estate manages approximately 13 hectares of vineyards, with additional hectares under direct management and partnerships. In Agro Aversano, they cultivate Asprinio vines using the traditional alberata system, where vines are trained to grow up to 15 meters high on poplar trees—a method that allows for optimal sun exposure and air circulation.In Campi Flegrei, the vineyards benefit from sandy, volcanic soils that are resistant to phylloxera, allowing for the cultivation of ungrafted Falanghina and Piedirosso vines. The Sorrento Peninsula vineyards are known for producing grapes for their Gragnano and Lettere wines, utilizing a blend of indigenous red varieties.

The winery emphasizes minimal intervention and the expression of terroir in its winemaking practices. For their sparkling Asprinio d’Aversa 'Trentapioli', they employ the Martinotti (Charmat) method, allowing the wine to mature on its lees for at least 180 days, resulting in a fresh and vibrant profile. Their still wines, such as the 'Settevulcani' Falanghina and Piedirosso, are vinified to highlight the mineral and saline qualities imparted by the volcanic soils. The 'Otto Uve' Gragnano is a semi-sparkling red wine made from a blend of eight native grape varieties, showcasing the region's winemaking heritage.

The wines of Salvatore Martusciello showcase Campania’s indigenous grape varieties and diverse terroirs. The Trentapioli Asprinio d’Aversa DOC is a sparkling wine made using the Martinotti method, offering citrus aromas, floral nuances, and crisp acidity, and is crafted from vines trained in the traditional alberata system. The Settevulcani Falanghina dei Campi Flegrei DOC expresses the volcanic soils of Campi Flegrei with bright acidity and mineral character, while the Settevulcani Piedirosso displays red berry fruit and a saline edge typical of its coastal origins. The Otto Uve Gragnano DOC is a semi-sparkling red wine made from a blend of eight local grape varieties, celebrated for its vibrant fruit and affinity with classic Neapolitan cuisine.